benzene-induced changes in hematological parameters and urinary trans, trans-muconic acid among gasoline station workers
نویسندگان
چکیده
[no abstract available]
منابع مشابه
Occupational exposure to benzene and changes in hematological parameters and urinary trans, trans-muconic acid.
BACKGROUND For its toxicity, benzene exposure is one of the main health concerns for high risk occupations like gasoline station workers. However, there is little knowledge about the effect of benzene metabolites on hematological parameters. OBJECTIVE To evaluate the correlation between the urinary level of trans, trans-muconic acid (t, t-MA), a benzene metabolite, and some hematological para...
متن کاملoccupational exposure to benzene and changes in hematological parameters and urinary trans, trans-muconic acid
background: for its toxicity, benzene exposure is one of the main health concerns for high risk occupations like gasoline station workers. however, there is little knowledge about the effect of benzene metabolites on hematological parameters. objective: to evaluate the correlation between the urinary level of trans, trans-muconic acid (t, t-ma), a benzene metabolite, and some hematological para...
متن کاملUrinary trans,trans-muconic acid as an indicator of exposure to benzene in cigarette smokers.
Epidemiological studies have shown an association between cigarette smoking and increased risk of myeloid leukemia in smokers. In evaluating this link it is important to note that cigarette smoke contains benzene, among other carcinogens. Since chronic benzene, among other carcinogens. Since chronic benzene exposure causes acute myeloid leukemia in humans, we aimed to determine the uptake and m...
متن کاملUrinary trans,trans-Muconic Acid as an Indicator of Exposure to Benzene in Cigarette Smokers1
Epidemiological studies have shown an association between cigarette smoking and increased risk of myeloid leukemia in smokers. In evaluating this link it is important to note that cigarette smoke contains benzene, among other carcinogens. Since chronic benzene exposure causes acute myeloid leukemia in humans, we aimed to determine the uptake and metabolic activation of benzene from cigarette sm...
متن کاملHigh-performance liquid chromatographic determination of urinary trans, trans-muconic acid excreted by workers occupationally exposed to benzene.
OBJECTIVE To investigate the relationship between trans, trans-muconic acid (ttMA) as benzene metabolite of occupational workers and benzene concentration in air. METHODS A rapid and sensitive high-performance liquid chromatography was developed to determine the level of urinary ttMA. ttMA was extrated from urinary samples in liquid-liquid phase a ODS (2) (5u) column (phi 4.6 mm x 150 mm) and...
متن کامل[Assessment of urinary trans, trans-muconic acid as a biomarker of exposure to benzene].
OBJECTIVE To assess the use of trans, trans-muconic acid as a biomarker of occupational exposure to benzene. METHODS Trans, trans-muconic acid in urine samples of exposed (exposed group, n=36) and non-exposed (non-exposed group, n=116) workers to benzene. Urinary levels of trans, trans-muconic acid were quantified by high-performance liquid chromatography. The study sample consisted of subjec...
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عنوان ژورنال:
international journal of occupational and environment medicineجلد ۴، شماره ۲ April، صفحات ۲۱۸-۱۰۹
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